Page 39 - Livre électronique du congrès AFMAPATH 2024
P. 39
to septal and nonseptal thickening, multiple hilo-mediastinal nodes and homogeneous
hepatomegaly without suspicious lesions.
The biopsy of the subcutaneous nodule of the right leg showed lesions of lobular panniculitis
made of a polymorphic inflammatory infiltrate of low density, with the presence of polynuclear
neutrophils evoking the panniculitis of Weber Christian.
The diagnosis of Weber-Christian disease with multisystem involvement was made.
The patient had ceftriaxone (2g/jour) and Ciprofloxacin (500 mg*2/jour) during 15 days, with
methylprednisolone during 3 days.
The evolution was marked by the apyrexia and regression of the ocular and scrotal edema.
Conclusion :
Weber Christian disease is a rare inflammatory disease of unknown etiology. The diagnosis can
only be made after eliminating other causes of lobular panniculitis. The prognosis is determined
by visceral lesions. More studies are needed for a better understanding of this multisystemic
disease.
38 | P a ge
